Bacterial Biofilms: Survival Mechanisms and Antibiotic Resistance

Persistence of antibiotic resistance plasmids in bacterial biofilms

The emergence and spread of antibiotic resistance is a crisis in health care today. Antibiotic resistance is often horizontally transferred to susceptible bacteria by means of multidrug resistance plasmids that may or may not persist in the absence of antibiotics. Because bacterial pathogens often grow as biofilms, there is a need to better understand the evolution of plasmid persistence in the...

antibiotic prescription and bacterial resistance

Antibiotic resistance of bacteria in biofilms.

Bacteria that adhere to implanted medical devices or damaged tissue can encase themselves in a hydrated matrix of polysaccharide and protein, and form a slimy layer known as a biofilm. Antibiotic resistance of bacteria in the biofilm mode of growth contributes to the chronicity of infections such as those associated with implanted medical devices. The mechanisms of resistance in biofilms are di...

Bacterial antibiotic resistance pdf

Two page summaries of cross-cutting and bacteriaspecific antibiotic resistance topics. The first section provides context and an overview of antibiotic resistance.Antimicrobial resistance: global report on surveillance. Resistance to antibacterial drugs in selected bacteria of international concern. Previously harmful agents that is known today as antimicrobial resistance. Currently antimicrobi...

Bacterial vaccines and antibiotic resistance

Spread of antibiotic resistance is mediated by clonal lineages of bacteria that besides being resistant also possess other properties promoting their success. Some vaccines already in use, such as the pneumococcal conjugate vaccines, have had an effect on these successful clones, but at the same time have allowed for the expansion and resistance evolution of previously minor clones not covered ...